I think Amazon is a tough competitor. It would be very difficult to grow a business that large to compete directly with them.
That said, there are tons of niche markets available in e-commerce that can make you money. All it takes is hard work and the right tools.
I’ve found a neat product called SBI! Not only does it give you all the technical tools to build a successful website, but it also gives you direction on how to drive traffic to your site. Check out the link below.